Size :50ug
Clone Number:
Aliases:Fxn antibody; FrdaFrataxin antibody; mitochondrial antibody; Fxn antibody; EC 1.16.3.1) [Cleaved into: Frataxin intermediate form; Frataxin mature form] antibody
Product Type:Polyclonal Antibody
Immunogen Species:Mus musculus (Mouse)
UniProt ID:O35943
Immunogen:Recombinant Mouse Frataxin, mitochondrial protein (78-207AA)
Raised in:Rabbit
Species Reactivity:Mouse
Tested Applications:ELISA
Background:Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:Fxn
Research Areas:Tags & Cell Markers; Metabolism; Signal transduction