Size :50ul
Clone Number:
Aliases:Chfz-1 antibody; Dfrizzled-1 antibody; DKFZp564G072 antibody; FLJ95923 antibody; Frizzled 1 antibody; Frizzled homolog 1 (Drosophila) antibody; Frizzled homolog 1 antibody; Frizzled-1 antibody; Fz receptor 1 antibody; Fz-1 antibody; Fz1 antibody; FZD1 antibody; FZD1_HUMAN antibody; FzE1 antibody; hFz1 antibody; Rfz1 antibody; Wnt receptor antibody; Xfrizzled-1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9UP38
Immunogen:Synthetic peptide of Human FZD1
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000
Background:Members of the ‘frizzled’ gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:FZD1
Research Areas:Cancer;Signal transduction?Stem cells