Size :50ug
Clone Number:
Aliases:GPM6A antibody; GPM6A_HUMAN antibody; M6a antibody; Neuronal membrane glycoprotein M6-a antibody; Neuronal membrane glycoprotein M6-a, antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P51674
Immunogen:Recombinant Human Neuronal membrane glycoprotein M6-a protein (149-213AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GPM6A
Research Areas:Neuroscience