Size :50ul
Clone Number:
Aliases:AAT1 antibody; Alanine aminotransferase 1 antibody; Alanine aminotransferase antibody; ALAT1_HUMAN antibody; ALT1 antibody; Glutamate pyruvate transaminase 1 antibody; Glutamic alanine transaminase 1 antibody; Glutamic pyruvate transaminase (alanine aminotransferase) antibody; Glutamic pyruvic transaminase 1 antibody; Glutamic–alanine transaminase 1 antibody; Glutamic–pyruvic transaminase 1 antibody; GPT 1 antibody; gpt antibody; GPT1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P24298
Immunogen:Synthetic peptide of Human GPT
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50
Background:This gene encodes cytosolic alanine aminotransaminase 1 (ALT1), also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GPT
Research Areas:Metabolism;Signal transduction