Size :50ug
Clone Number:
Aliases:Core histone macro H2A2.2 antibody; Core histone macro-H2A.2 antibody; Core histone macroH2A2.2 antibody; H2A histone family member Y2 antibody; H2AFY2 antibody; H2AW_HUMAN antibody; Histone macroH2A2 antibody; Macro H2A.2 antibody; Macro H2A2 antibody; MacroH2A.2 antibody; MacroH2A2 antibody; mH2A2 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9P0M6
Immunogen:Recombinant Human Core histone macro-H2A.2 protein (1-260AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:
Background:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:H2AFY2
Research Areas:Epigenetics and Nuclear Signaling