Size:100ug
Purification:protein A+G purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:3C12
Isotype:IgG1
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
Immunogen:MHC class I antigen G
Synonyms:HLA 6.0, HLA G, HLA G antigen, HLAG, HLA-G, MHC class I antigen G, MHC G
Observed MW:38 kDa
Uniprot ID:P17693
Reactivity:Human
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:2000-1:10000; IHC: 1:50-1:200
Gene ID:3135
Research Area:Immunology