Size :50ul
Clone Number:
Aliases:Adenomatous Polyposis Coli antibody; Adenomatous polyposis coli protein antibody; Apc antibody; APC_HUMAN antibody; CC1 antibody; Deleted in polyposis 2.5 antibody; DP2 antibody; DP2.5 antibody; DP3 antibody; FAP antibody; FPC antibody; GS antibody; Protein APC antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P25054
Immunogen:Synthetic peptide of Human APC
Raised in:Rabbit
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100
Background:This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:APC
Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer?Cardiovascular?Cell biology;Stem cells