Size :50ug
Clone Number:
Aliases:Basic helix loop helix domain containing class B 8 antibody; Basic helix loop helix family member a15 antibody; BHA15_HUMAN antibody; Bhlha15 antibody; bHLHB8 antibody; Class A basic helix-loop-helix protein 15 antibody; Class B basic helix-loop-helix protein 8 antibody; Class II bHLH protein MIST1 antibody; intestine and stomach expression 1 antibody; MIST 1 antibody; MIST-1 antibody; MIST1 antibody; Muscle antibody; Muscle intestine and stomach expression 1 antibody; protein MIST1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q7RTS1
Immunogen:Recombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:
Background:Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5′-CANNTG-3′ (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:BHLHA15
Research Areas:Epigenetics and Nuclear Signaling