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ACKR1 Antibody – Cat. #: CSB-PA624105LA01HU Gene Bio Systems

Original price was: $ 431,60.Current price is: $ 129,48.

SKU: mode_6912800424036 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size :50ug

Clone Number:

Aliases:ACKR1 antibody; Atypical chemokine receptor 1 antibody; CCBP1 antibody; CD234 antibody; DARC antibody; Dfy antibody; Duffy antigen/chemokine receptor antibody; duffy blood group antibody; Duffy blood group antigen antibody; Duffy blood group chemokine receptor antibody; DUFFY_HUMAN antibody; FY antibody; Fy glycoprotein antibody; Glycoprotein D antibody; GPD antibody; GpFy antibody; Plasmodium vivax receptor antibody; WBCQ1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16570

Immunogen:Recombinant Human Atypical chemokine receptor 1 protein (1-63AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200

Background:Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and also for the malaria parasites P.vivax and P.knowlesi. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ACKR1

Research Areas:Cardiovascular; Immunology; Microbiology; Signal transduction

Prompt Shipping and professional packaging

Because of our long-standing partnership in a long-standing partnership with UPS, FedEx, DHL and a variety of other leading global carriers, we can provide a variety of shipping options. Our warehouse staff are highly trained to package your goods exactly as per the specifications we offer. Your goods are thoroughly checked and securely secured prior to shipment. We deliver to thousands of customers every day from all over the world. This shows that we're committed to being the largest retailer online in the world. The warehouses and centers of distribution are situated in Europe, as well as the USA.

Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

ACKR1 Antibody – Cat. #: CSB-PA624105LA01HU Gene Bio Systems

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