Size:100ug
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:8D6
Isotype:IgG2a
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions(pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.
Isoform 2: the cellular form also has ecto-5′-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
Immunogen:acid phosphatase, prostate
Synonyms:Acid phosphatase, prostate, ACP 3, ACP3, ACPP, PAP, Prostatic acid phosphatase
Observed MW:48 kDa
Uniprot ID:P15309
Reactivity:Human, rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:200-1:2000; IHC: 1:20-1:200
Gene ID:55
Research Area:Cancer, Immunology, Metabolism