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CHMP2A Antibody, FITC conjugated – Cat. #: CSB-PA04524C0Rb Gene Bio Systems

Original price was: $ 431,60.Current price is: $ 129,48.

SKU: mode_6912646807652 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size :50ug

Clone Number:

Aliases:BC 2 antibody; BC2 antibody; Charged multivesicular body protein 2a antibody; CHM2A_HUMAN antibody; CHMP2 antibody; CHMP2a antibody; Chromatin modifying protein 2a antibody; Chromatin-modifying protein 2a antibody; hVps2 1 antibody; hVps2-1 antibody; putative breast adenocarcinoma marker antibody; Putative breast adenocarcinoma marker BC-2 antibody; Putative breast adenocarcinoma marker BC2 antibody; Vacuolar protein sorting associated protein 2 1 antibody; Vacuolar protein sorting-associated protein 2-1 antibody; Vps2 1 antibody; VPS2 antibody; Vps2-1 antibody; VPS2A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43633

Immunogen:Recombinant Human Charged multivesicular body protein 2a protein (1-222AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CHMP2A

Research Areas:Signal transduction

Prompt Shipping and professional packaging

Because of our long-standing partnership in a long-standing partnership with UPS, FedEx, DHL and a variety of other leading global carriers, we can provide a variety of shipping options. Our warehouse staff are highly trained to package your goods exactly as per the specifications we offer. Your goods are thoroughly checked and securely secured prior to shipment. We deliver to thousands of customers every day from all over the world. This shows that we're committed to being the largest retailer online in the world. The warehouses and centers of distribution are situated in Europe, as well as the USA.

Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

CHMP2A Antibody, FITC conjugated – Cat. #: CSB-PA04524C0Rb Gene Bio Systems

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