Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Immunogen:chromatin modifying protein 2B
Synonyms:
Observed MW:28 kDa
Uniprot ID:Q9UQN3
Reactivity:Human, Mouse
Tested Application:ELISA, WB, IF, IHC
Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:50 – 1:200
Gene ID:25978
Research Area:Neuroscience