Size :50ug
Clone Number:
Aliases:Beta GR antibody; Beta-glucan receptor antibody; BGR antibody; C type calcium dependent carbohydrate recognition domain lectin superfamily member 12 antibody; C type lectin domain family 7 member a antibody; C-type lectin domain family 7 member A antibody; C-type lectin superfamily member 12 antibody; CANDF4 antibody; CLC7A_HUMAN antibody; CLEC7A antibody; CLEC7A protein antibody; Clecsf12 antibody; DC-associated C-type lectin 1 antibody; Dectin 1 antibody; DECTIN 1 receptor antibody; Dectin-1 antibody; Dectin1 antibody; Dendritic cell associated C type lectin 1 antibody; Dendritic cell-associated C-type lectin 1 antibody; Lectin like receptor 1 antibody; Putative transmembrane protein dectin 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9BXN2
Immunogen:Recombinant Human C-type lectin domain family 7 member A protein (1-44AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CLEC7A
Research Areas:Immunology