Size :50ul
Clone Number:
Aliases:C3 binding protein antibody; C3b/C4b receptor antibody; C3BR antibody; C4BR antibody; CD 35 antibody; CD35 antibody; CD35 antigen antibody; complement component (3b/4b) receptor 1 (Knops blood group) antibody; complement component (3b/4b) receptor 1 including Knops blood group system antibody; Complement component receptor 1 antibody; Complement receptor 1 antibody; Complement receptor type 1 antibody; CR 1 antibody; CR1 antibody; CR1_HUMAN antibody; KN antibody; Knops blood group antigen antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P17927
Immunogen:Synthetic peptide of Human CR1
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100
Background:This gene is a member of the receptors of complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CR1
Research Areas:Immunology;Stem cells