Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Immunogen:diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)
Synonyms:DBI, ACBD1, ACBP, CCK-RP, EP, acyl-CoA-binding protein
Observed MW:12 kDa
Uniprot ID:P07108
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200
Gene ID:1622
Research Area:Metabolism