Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:3′-5′-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3′ end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3′. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem(ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
Immunogen:DIS3 mitotic control homolog(S. cerevisiae)-like 2
Synonyms:FAM6A
Observed MW:65 kDa/99 kDa
Uniprot ID:Q8IYB7
Reactivity:Human, Mouse
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:129563
Research Area:Metabolism