Size :50ul
Clone Number:
Aliases:ARVD11 antibody; Cadherin family member 2 antibody; CDHF2 antibody; Desmocollin 3 antibody; Desmocollin-2 antibody; Desmocollin-3 antibody; Desmocollin2 antibody; Desmosomal glycoprotein II and III antibody; Desmosomal glycoprotein II antibody; Desmosomal glycoprotein II/III antibody; Desmosomal glycoprotein III antibody; DG2 antibody; DGII/III antibody; DKFZp686I11137 antibody; DSC 2 antibody; DSC2 antibody; DSC2_HUMAN antibody; DSC3 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q02487
Immunogen:Synthetic peptide of Human DSC2
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200
Background:The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:DSC2
Research Areas:Cardiovascular;Signal transduction