Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5′-TTTC[CG]CGC-3′ found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters(PubMed:20176812).
Immunogen:E2F transcription factor 1
Synonyms:RBBP3
Observed MW:55 kDa
Uniprot ID:Q01094
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, IHC, WB
Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200
Gene ID:1869
Research Area:Cell Division and Proliferation, Metabolism