Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Immunogen:eukaryotic translation initiation factor 4 gamma, 1
Synonyms:EIF4F, EIF4G, EIF4GI
Observed MW:230 kDa
Uniprot ID:Q04637
Reactivity:Human
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:50 – 1:200
Gene ID:1981
Research Area:Neuroscience, Metabolism