Size :50ul
Clone Number:
Aliases:COXPD17 antibody; elaC homolog 2 (E. coli) antibody; ElaC homolog protein 2 antibody; elaC ribonuclease Z 2 antibody; elaC, E. coli, homolog of, 2 antibody; ELAC2 antibody; ELC2 antibody; FLJ10530 antibody; FLJ36693 antibody; FLJ42848 antibody; Heredity prostate cancer protein 2 antibody; HPC2 antibody; putative prostate cancer susceptibility protein HPC2/ELAC2 antibody; Ribonuclease Z 2 antibody; Ribonuclease Z, long form antibody; Ribonuclease Z2 antibody; RNase Z 2 antibody; RNase Z2 antibody; RNase ZL antibody; RNZ2_HUMAN antibody; tRNA 3 endonuclease 2 antibody; tRNase Z (long form) antibody; tRNase Z 2 antibody; tRNase Z2 antibody; Zinc phosphodiesterase ELAC protein 2 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9BQ52
Immunogen:Fusion protein of Human ELAC2
Raised in:Rabbit
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200
Background:The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ELAC2
Research Areas:Epigenetics and Nuclear Signaling;Cancer