Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A(PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D(PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase(By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor(ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
Immunogen:endosulfine alpha
Synonyms:
Observed MW:19 kDa
Uniprot ID:O43768
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200
Gene ID:2029
Research Area:Neuroscience