Size :50ul
Clone Number:
Aliases:Exendin-4 antibody; Exenatide antibody
Product Type:Polyclonal Antibody
Immunogen Species:Heloderma suspectum (Gila monster)
UniProt ID:P26349
Immunogen:Synthetic peptide of Heloderma suspectum Exendin 4
Raised in:Rabbit
Species Reactivity:Heloderma suspectum
Tested Applications:ELISA; ELISA:1:1000-1:2000
Background:Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:
Research Areas:Others