Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
Immunogen:fibrillarin
Synonyms:FIB1, FLRN
Observed MW:37 kDa
Uniprot ID:P22087
Reactivity:Human, Mouse
Tested Application:ELISA, IF, IHC, WB, IP
Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:50 – 1:200; IP? 1:20 – 1:50
Gene ID:2091
Research Area:Metabolism