Size :50ul
Clone Number:
Aliases:110 kDa actin filament associated protein antibody; 110 kDa actin filament-associated protein antibody; Actin filament associated protein 1 antibody; Actin filament associated protein 110 kDa antibody; Actin filament-associated protein 1 antibody; AFAP 1 antibody; AFAP 110 antibody; AFAP antibody; AFAP-110 antibody; Afap1 antibody; AFAP1_HUMAN antibody; AFAP110 antibody; FLJ56849 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q8N556
Immunogen:Recombinant Human Actin filament-associated protein 1 protein (461-730AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjugate:Non-conjugated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:AFAP1
Research Areas:Signal transduction