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AGS3 antibody , Cat. # FNab00221 Gene Bio Systems

Original price was: $ 470,00.Current price is: $ 141,00.

SKU: mode_6918448906340 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).

Immunogen:G-protein signaling modulator 1(AGS3-like, C. elegans)

Synonyms:AGS3, DKFZp727I051, GPSM1

Observed MW:72 kDa

Uniprot ID:Q86YR5

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, IF, WB

Recommended dilution:WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200

Gene ID:26086

Research Area:Cell Division and Proliferation, Signal Transduction, Developmental biology

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Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

AGS3 antibody , Cat. # FNab00221 Gene Bio Systems

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