Size :50ul
Clone Number:
Aliases:BOD1 antibody; FAM44BBiorientation of chromosomes in cell division protein 1 antibody; Biorientation defective protein 1 antibody; Protein FAM44B antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q96IK1
Immunogen:Synthetic peptide of Human BOD1
Raised in:Rabbit
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100
Background:Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis. Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:BOD1
Research Areas:Epigenetics and Nuclear Signaling;Cell biology