Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Immunogen:CD59 molecule, complement regulatory protein
Synonyms:MIC11, MIN1, MIN2, MIN3, MSK21
Observed MW:18-20 kDa
Uniprot ID:P13987
Reactivity:Human
Tested Application:ELISA, WB, IHC, FC, IF
Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID:966
Research Area:Stem Cells, Immunology, Signal Transduction