Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).
Immunogen:COMM domain containing 5
Synonyms:
Observed MW:25-28 kDa
Uniprot ID:Q9GZQ3
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:2000
Gene ID:54951
Research Area:Signal Transduction, Metabolism, Epigenetics