Size :100ul
Clone Number:
Aliases:Cellular retinoic acid binding protein 2 antibody; Cellular retinoic acid binding protein II antibody; Cellular retinoic acid-binding protein 2 antibody; Cellular retinoic acid-binding protein II antibody; CRABP II antibody; CRABP-II antibody; Crabp2 antibody; CRABPII antibody; RABP2_HUMAN antibody; RBP6 antibody; Rretinoic acid-binding protein, cellular, type II antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P29373
Immunogen:Peptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2
Raised in:Rabbit
Species Reactivity:Human, Rat
Tested Applications:ELISA, WB; WB:1:500-1:1000
Background:
Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors “Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest.”
Budhu A.S., Noy N. Mol. Cell. Biol. 22:2632-2641(2002) “A ligand-activated nuclear localization signal in cellular retinoic acid binding protein-II.”
Sessler R.J., Noy N. Mol. Cell 18:343-353(2005)
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conjugate:Non-conjugated
Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CRABP2
Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction