Size :50ul
Clone Number:
Aliases:CST 6 antibody; CST6 antibody; Cystatin 6 antibody; Cystatin E antibody; Cystatin E/M antibody; Cystatin M antibody; Cystatin M/E antibody; Cystatin-6 antibody; Cystatin-E antibody; Cystatin-M antibody; Cystatin6 antibody; CystatinE antibody; CystatinM antibody; Cysteine proteinase inhibitor antibody; CYTM_HUMAN antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q15828
Immunogen:Fusion protein of Human CST6
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200
Background:The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CST6
Research Areas:Cell biology