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CTCFL Antibody – Cat. #: CSB-PA818824ESR2HU Gene Bio Systems

Original price was: $ 431,60.Current price is: $ 129,48.

SKU: mode_6913368424548 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size :50ul

Clone Number:

Aliases:BORIS like protein antibody; Brother of the regulator of imprinted sites antibody; Cancer/testis antigen 27 antibody; CCCTC binding factor (zinc finger protein) like antibody; CCCTC-binding factor antibody; CT27 antibody; CTCF paralog antibody; CTCF T antibody; CTCF-like protein antibody; Ctcfl antibody; CTCFL_HUMAN antibody; dJ579F20.2 antibody; HMG 1L1 antibody; HMGB1L1 antibody; MGC163358 antibody; MGC169105 antibody; MGC169106 antibody; Putative high mobility group protein 1 like 1 antibody; Putative high mobility group protein B1 like 1 antibody; Transcriptional repressor CTCFL antibody; Zinc finger protein CTCF-T antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NI51

Immunogen:Recombinant Human Transcriptional repressor CTCFL protein (1-270AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 \’Arg-3\’ to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CTCFL

Research Areas:Epigenetics and Nuclear Signaling; Cancer

Prompt Shipping and professional packaging

Because of our long-standing partnership in a long-standing partnership with UPS, FedEx, DHL and a variety of other leading global carriers, we can provide a variety of shipping options. Our warehouse staff are highly trained to package your goods exactly as per the specifications we offer. Your goods are thoroughly checked and securely secured prior to shipment. We deliver to thousands of customers every day from all over the world. This shows that we're committed to being the largest retailer online in the world. The warehouses and centers of distribution are situated in Europe, as well as the USA.

Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

CTCFL Antibody – Cat. #: CSB-PA818824ESR2HU Gene Bio Systems

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