Size :100ul
Clone Number:
Aliases:Alpha E-catenin antibody; Cadherin associated protein 102kDa antibody; Cadherin associated protein antibody; Cadherin-associated protein antibody; CAP 102 antibody; CAP102 antibody; Catenin (cadherin associated protein) alpha 1 102kDa antibody; Catenin (cadherin associated protein), alpha 1, 102kDa antibody; Catenin alpha 1 antibody; Catenin alpha-1 antibody; CTNA1_HUMAN antibody; CTNNA 1 antibody; Ctnna1 antibody; FLJ36832 antibody; FLJ52416 antibody; MDPT2 antibody; NY REN 13 antigen antibody; OTTHUMP00000224141 antibody; OTTHUMP00000224147 antibody; Renal carcinoma antigen NY REN 13 antibody; Renal carcinoma antigen NY-REN-13 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P35221
Immunogen:Peptide sequence around aa. 639~643 (D-D-S-D-F) derived from Human a-catenin.
Raised in:Rabbit
Species Reactivity:Human, Mouse
Tested Applications:ELISA, WB; WB:1:500-1:1000
Background:Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.
Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765
Drees, F. et al. (2005) Cell 123, 903-915.
Yamada, S. et al. (2005) Cell 123, 889-901.
Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Conjugate:Non-conjugated
Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CTNNA1
Research Areas:Cancer;Signal transduction?Stem cells