Size :50ug
Clone Number:
Aliases:Dio3 antibody; Itdi3 antibody; Txdi3 antibody; Thyroxine 5-deiodinase antibody; EC 1.21.99.3 antibody; 5DIII antibody; DIOIII antibody; Type 3 DI antibody; Type III iodothyronine deiodinase antibody
Product Type:Polyclonal Antibody
Immunogen Species:Rattus norvegicus (Rat)
UniProt ID:P49897
Immunogen:Recombinant Rat Thyroxine 5-deiodinase protein (37-278AA)
Raised in:Rabbit
Species Reactivity:Rat
Tested Applications:ELISA
Background:Responsible for the deiodination of T4 (3,5,3\’,5\’-tetraiodothyronine) into RT3 (3,3\’,5\’-triiodothyronine) and of T3 (3,5,3\’-triiodothyronine) into T2 (3,3\’-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:Dio3
Research Areas:Neuroscience; Cancer; Metabolism; Signal transduction