Size :50ul
Clone Number:
Aliases:DKFZp686A1451 antibody; eIF 4 gamma 1 antibody; eIF 4G 1 antibody; eIF 4G1 antibody; eIF-4-gamma 1 antibody; eIF-4G 1 antibody; eIF-4G1 antibody; EIF4 gamma antibody; EIF4F antibody; EIF4G antibody; EIF4G1 antibody; EIF4GI antibody; Eukaryotic translation initiation factor 4 gamma 1 antibody; IF4G1_HUMAN antibody; p220 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q04637
Immunogen:Synthetic peptide of Human EIF4G1
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100
Background:The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:EIF4G1
Research Areas:Epigenetics and Nuclear Signaling