Size :50ug
Clone Number:
Aliases:3 keto acyl CoA synthase ELOVL1 antibody; 3-keto acyl-CoA synthase ELOVL1 antibody; CGI 88 antibody; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 antibody; Elongation of very long chain fatty acids like 1 antibody; Elongation of very long chain fatty acids protein 1 antibody; ELOV1_HUMAN antibody; ELOVL 1 antibody; ELOVL FA elongase 1 antibody; ELOVL fatty acid elongase 1 antibody; ELOVL1 antibody; Ssc1 antibody; Ssc1; mouse; homolog of antibody; very long chain 3 oxoacyl CoA synthase 1 antibody; Very-long-chain 3-oxoacyl-CoA synthase 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9BW60
Immunogen:Recombinant Human Elongation of very long chain fatty acids protein 1 protein (82-175AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:
Background:Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ELOVL1
Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction