Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Tyrosine phosphatase that specifically dephosphorylates ‘Tyr-142’ of histone H2AX(H2AXY142ph). ‘Tyr-142’ phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye(By similarity).
Immunogen:eyes absent homolog 4(Drosophila)
Synonyms:
Observed MW:67 kDa
Uniprot ID:O95677
Reactivity:Human, Mouse
Tested Application:ELISA, WB, IF
Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200
Gene ID:2070
Research Area:Neuroscience, Cardiovascular, Metabolism, Developmental biology