Size :50ul
Clone Number:
Aliases:coagulation factor II (thrombin) antibody; Coagulation factor II antibody; F2 antibody; Factor II antibody; Prepro coagulation factor II antibody; Prothrombin antibody; prothrombin B-chain antibody; PT antibody; RPRGL2 antibody; serine protease antibody; THPH1 antibody; THRB antibody; THRB_HUMAN antibody; Thrombin heavy chain antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P00734
Immunogen:Synthetic peptide of Human F2
Raised in:Rabbit
Species Reactivity:Human, Mouse, Rat
Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:20-1:100
Background:Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:F2
Research Areas:Cardiovascular?Cell biology;Signal transduction