Size :50ug
Clone Number:
Aliases:ALPS 1A antibody; ALPS1A antibody; APO 1 antibody; Apo 1 antigen antibody; APO 1 cell surface antigen antibody; Apo-1 antigen antibody; APO1 antibody; Apo1 antigen antibody; APO1 cell surface antigen antibody; Apoptosis antigen 1 antibody; Apoptosis mediating surface antigen FAS antibody; Apoptosis-mediating surface antigen FAS antibody; APT 1 antibody; APT1 antibody; CD 95 antibody; CD 95 antigen antibody; CD95 antibody; CD95 antigen antibody; Delta Fas antibody; Delta Fas/APO 1/CD95 antibody; Delta Fas/APO1/CD95 antibody; Fas (TNF receptor superfamily; member 6) antibody; FAS 1 antibody; FAS 827dupA antibody; Fas AMA antibody; Fas antibody; FAS Antigen antibody; Fas cell surface death receptor antibody; FAS1 antibody; FASLG receptor antibody; FASTM antibody; sFAS antibody; Surface antigen APO1 antibody; TNF receptor superfamily; member 6 antibody; TNFRSF 6 antibody; TNFRSF6 antibody; TNR6_HUMAN antibody; Tumor necrosis factor receptor superfamily member 6 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P25445
Immunogen:Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (26-171AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:
Background:Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:FAS
Research Areas:Cell biology; Immunology