Size :50ug
Clone Number:
Aliases:Fcmr antibody; Faim3 antibody; TosoFas apoptotic inhibitory molecule 3 antibody; IgM Fc fragment receptor antibody; Regulator of Fas-induced apoptosis Toso antibody
Product Type:Polyclonal Antibody
Immunogen Species:Mus musculus (Mouse)
UniProt ID:A1KXC4
Immunogen:Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA)
Raised in:Rabbit
Species Reactivity:Mouse
Tested Applications:
Background:May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:Fcmr
Research Areas:Others