Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Immunogen:FK506 binding protein 8, 38kDa
Synonyms:FKBP38
Observed MW:53 kDa
Uniprot ID:Q14318
Reactivity:Human, Mouse
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:23770
Research Area:Signal Transduction, Metabolism