Size :50ug
Clone Number:
Aliases:ABP 280 antibody; ABP-280 antibody; Actin-binding protein 280 antibody; Alpha filamin antibody; Alpha-filamin antibody; APBX antibody; CSBS antibody; CVD1 antibody; Endothelial actin binding protein antibody; Endothelial actin-binding protein antibody; Filamin 1 antibody; Filamin A alpha antibody; Filamin A antibody; Filamin-1 antibody; Filamin-A antibody; FLN antibody; FLN-A antibody; FLN1 antibody; FLNA antibody; FLNA_HUMAN antibody; FMD antibody; MNS antibody; NHBP antibody; Non muscle filamin antibody; Non-muscle filamin antibody; OPD antibody; OPD1 antibody; OPD2 antibody; XLVD antibody; XMVD antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P21333
Immunogen:Recombinant Human Filamin-A protein (1234-1462AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:FLNA
Research Areas:Signal transduction