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FLT3 (Ab-591) Antibody – Cat. #: CSB-PA546306 Gene Bio Systems

Original price was: $ 772,20.Current price is: $ 231,66.

SKU: mode_6912095584356 Category: Uncategorized Tag: PRIMARY ANTIBODIES

Description
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Size :100ul

Clone Number:

Aliases:CD 135 antibody; CD135 antibody; CD135 antigen antibody; Fetal liver kinase 2 antibody; FL cytokine receptor antibody; Flk 2 antibody; Flk2 antibody; Flt 3 antibody; FLT-3 antibody; Flt3 antibody; FLT3_HUMAN antibody; FMS like tyrosine kinase 3 antibody; Fms related tyrosine kinase 3 antibody; Fms-like tyrosine kinase 3 antibody; Growth factor receptor tyrosine kinase type III antibody; Ly-72 antibody; OTTHUMP0000004234 antibody; Receptor type tyrosine protein kinase FLT3 antibody; Stem cell tyrosine kinase 1 antibody; Stk 1 antibody; STK-1 antibody; Stk1 antibody; Tyrosine protein kinase receptor FLT3 antibody; Tyrosine-protein kinase receptor FLT3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P36888

Immunogen:Peptide sequence around aa.589~593 (Y-F-Y-V-D) derived from Human FLT3.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IF; WB:1:500-1:1000, IF:1:100-1:200

Background:FLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Sekine S et,al. (2008) J Immunol. ;180(12):8126-34
Pratz K et,al. (2008) Leuk Lymphoma. 2008 ;49(5):852-63.
Al Shaer L et,al. (2008) Br J Haematol. 141(4):483-93.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FLT3

Research Areas:Immunology;Signal transduction

Prompt Shipping and professional packaging

Because of our long-standing partnership in a long-standing partnership with UPS, FedEx, DHL and a variety of other leading global carriers, we can provide a variety of shipping options. Our warehouse staff are highly trained to package your goods exactly as per the specifications we offer. Your goods are thoroughly checked and securely secured prior to shipment. We deliver to thousands of customers every day from all over the world. This shows that we're committed to being the largest retailer online in the world. The warehouses and centers of distribution are situated in Europe, as well as the USA.

Note: Orders that contain more than one item are assigned a particular processing time, based on the individual item.

Prior to shipping We will inspect thoroughly the items you have ordered. The majority of orders will be sent within 48 hours. It is expected that delivery will take between three and seven days.

Returns

The inventory is always changing and we do not completely manage it due to the fact that several parties are involved, including our factory and warehouse. The actual stock levels can fluctuate at any moment. Be aware that it is possible that your order will run out of stock even after you've placed your order.

Our policy runs for 30 days. However, if 30 days have passed from the date you purchased the item, we cannot give you a refund or exchange.

To be eligible for a return, your product must be unopened and in the same condition as when you received it. The item must be in its original packaging.

FLT3 (Ab-591) Antibody – Cat. #: CSB-PA546306 Gene Bio Systems

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