Size:100ug
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:6A8
Isotype:IgG1
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Immunogen:folate receptor 1
Synonyms:Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1(adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha
Observed MW:38 kDa
Uniprot ID:P15328
Reactivity:Human
Tested Application:ELISA, WB,IHC
Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500
Gene ID:2348
Research Area:Immunology, Metabolism