Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements(IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells(ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Immunogen:forkhead box O4
Synonyms:AFX, AFX1, MLLT7
Observed MW:45-48kd
Uniprot ID:P98177
Reactivity:Human, Mouse
Tested Application:ELISA, WB, IF
Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200
Gene ID:4303
Research Area:Epigenetics, Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience