Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Immunogen:fibroblast growth factor receptor substrate 2
Synonyms:FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1
Observed MW:60 kDa
Uniprot ID:Q8WU20
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, IHC, WB, IF
Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Gene ID:10818
Research Area:Signal Transduction