Size :50ul
Clone Number:
Aliases:65 kDa glutamic acid decarboxylase antibody; DCE 2 antibody; DCE2 antibody; DCE2_HUMAN antibody; GAD 2 antibody; GAD 65 antibody; GAD-2 antibody; GAD-65 antibody; Gad2 antibody; Glutamate decarboxylase 2 (pancreas) antibody; Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa) antibody; Glutamate decarboxylase 2 antibody; Glutamate Decarboxylase 65 antibody; Glutamate decarboxylase 65 kDa isoform antibody; Glutamic Acid Decarboxylase 2 antibody; Glutamic Acid Decarboxylase 65 antibody; MGC161605 antibody; MGC161607 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q05329
Immunogen:Synthetic peptide of Human GAD2
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100
Background:This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GAD2
Research Areas:Neuroscience