Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Immunogen:glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Synonyms:GAD65
Observed MW:70 kDa
Uniprot ID:Q05329
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IF, IHC
Recommended dilution:WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:10 – 1:100
Gene ID:2572
Research Area:Neuroscience, Metabolism, Epigenetics