Size :50ul
Clone Number:
Aliases:AXL receptor tyrosine kinase ligand antibody; AXL stimulatory factor antibody; AXLLG antibody; AXS F antibody; AXSF antibody; DKFZp666G247 antibody; FLJ34709 antibody; Gas 6 antibody; GAS-6 antibody; Gas6 antibody; GAS6_HUMAN antibody; Growth arrest specific 6 antibody; Growth arrest-specific protein 6 antibody; Growth-arrest-specific protein 6 antibody; Growth-arrest-specific protein 6 precursor antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q14393
Immunogen:Synthetic peptide of Human GAS6
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50
Background:This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GAS6
Research Areas:Cardiovascular;Signal transduction?Stem cells