Size :100ul
Clone Number:
Aliases:Conjugase antibody; folylpolygammaglutamyl hydrolase antibody; gamma glutamyl hydrolase antibody; Gamma-Glu-X carboxypeptidase antibody; Gamma-glutamyl hydrolase (conjugase; folylpolygammaglutamyl hydrolase) antibody; Gamma-glutamyl hydrolase antibody; GGH antibody; GGH_HUMAN antibody; gH antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q92820
Immunogen:Synthesized peptide derived from internal of Human GGH.
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB; WB:1:500-1:3000
Background:Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996).
Yin D., Gene 238:463-470(1999).
Basrur V., J. Proteome Res. 2:69-79(2003).
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GGH
Research Areas:Metabolism;Signal transduction