Size :100ul
Clone Number:
Aliases:Acid beta galactosidase antibody; Acid beta-galactosidase antibody; Beta galactosidase 1 antibody; Beta galactosidase antibody; Beta-galactosidase antibody; BGAL_HUMAN antibody; EBP antibody; EBP; included antibody; Elastin receptor 1 (67kD) antibody; Elastin receptor 1 67kDa antibody; Elastin receptor 1 antibody; Elastin receptor 1; included antibody; Elastin-binding protein; included antibody; ELNR1 antibody; Galactosidase beta 1 antibody; GLB 1 antibody; GLB1 antibody; Lactase antibody; MPS4B antibody; S-GAL; included antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P16278
Immunogen:Synthesized peptide derived from internal of Human GLB1.
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB; WB:1:500-1:3000
Background:Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. soform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.
Oshima A., Biochem. Biophys. Res. Commun. 157:238-244(1988) [PubMed: 3143362].
Morreau H., J. Biol. Chem. 264:20655-20663(1989) [PubMed: 2511208].
Yamamoto Y., DNA Cell Biol. 9:119-127(1990) [PubMed: 2111707].
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:GLB1
Research Areas:Metabolism;Signal transduction